Commentary: Crawling toward heart transplantation and beyond

Commentary: toward a psychodynamic understanding of filicide--beyond psychosis and into the heart of darkness.

Much of the literature on filicide explores acute psychosis, sociopathy, or malignant narcissism (psychiatrically ill versus not psychiatrically ill) as primary explanations of why parents kill children. In this issue, Hatters Friedman et al. review the literature on acute psychiatric symptoms in an effort to identify key risk factors for filicide that might have predictive value. In this comme...

Toward and beyond lysosomes.

Invited commentary: beyond frequencies and coefficients--toward meaningful descriptions for life course epidemiology.

The expected doubling of the elderly population in the United States by year 2030 poses a major challenge to public health and medical care systems because of limited and progressive diminution of resources for public health and medical care for the elderly (1). This challenge highlights the urgent need for effective programs and policies aimed at the prevention of diseases and maintenance of h...

Uterus transplantation and beyond

Uterus transplantation is today the only available treatment for absolute uterine factor infertility which is caused by either congenital/surgical uterine absence or that a present uterus is non-functioning. Structured animal-based research, from rodents to nonhuman primates, was the scientific basis for a successful introduction of uterus transplantation as a clinical procedure. The patient gr...

Crawling Toward a Diagnosis: Vesicles and Thrombocytopenia in a Neonate.

C A S E A previously healthy 25-day-old boy presented to a tertiary children’s hospital with a diffuse vesicular rash worsening over the previous 2 weeks. Per parental report, the rash was not accompanied by any other symptoms and did not appear to be pruritic or painful; specifically, he had no history of fever and was formula feeding well. The infant was the product of a full-term pregnancy, ...